Abstract:Vitamin B6 (VB6) is a generic term referring to six interconvertiblecompounds,pyridoxine,pyridoxal,pyridoxamine and their phosphorylated derivatives,pyridoxine 5′-phosphate,pyridoxal 5′-phosphate and pyridoxamine 5′-phosphate.Pyridoxal 5′-phosphate is the catalytically active form of VB6,andacts as cofactor in more than 140 different enzyme reactions.VB6 is synthesized de novo by two different enzymatic pathways,the DXP (1′-deoxy-D-xylulose-5′-phosphate)- dependent pathway of E.coli and a few other bacteria,and the DXP- independent pathway found in almost all other organisms,except for animals.In addition to the de novo pathways,another pathway is found in all organisms,and functions to convert the six different VB6 forms between each other.This pathway is called the “salvage pathway”.This article summarizes the current knowledge on the de novo synthetic pathway and the salvage pathway of VB6 in plants.