植物中lncRNAs的研究进展
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国家自然科学基金(31560560);


Advances of Long Noncoding RNA in Plants
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    摘要:

    随着高通量测序技术的飞速发展,越来越多的lncRNAs在植物中被发现,并具有生物学功能。lncRNAs是长度大于200个核苷酸且不具备编码蛋白质功能的一类RNA分子。目前lncRNAs在动物中的功能、作用机制等方面的研究较深入,lncRNAs不仅在表观遗传水平、转录水平、转录后水平上调控基因的表达,也参与诸多生命过程调控如基因组印迹、染色体重塑、转录激活等。在植物中虽有关于lncRNAs的研究,但由于缺乏有效的技术方法而相对滞后。该文就近几年来国内外关于植物lncRNAs的来源、结构特征、分类、功能等方面的研究进展进行综述,为进一步理解和研究植物中lncRNAs的功能和分子机制提供参考。

    Abstract:

    With the rapid development of highthroughput sequencing technology, more and more lncRNAs(Long noncoding RNA) which have biological functions were found in plants. lncRNAs are important noncoding RNA longer than 200 nucleotides. The researches on the function and mechanism of lncRNAs were more deeply in animals so far, not only in epigenetic level, transcription and posttranscription, but also playing important roles in wide ranges of biological processes such as genomic imprinting, chromatin remodeling, transcriptional activation. Compared to animals, some studies have to do with lncRNAs in plants, but the research of lncRNAs in plants is a little backward due to the lack of effective technologies and methods. Therefore, based on the latest advances on lncRNA recently, we reviewed the origin, structural characteristics, classification, molecular mechanism and function, which providing a guide for further study of function and molecular mechanism of lncRNAs in plants.

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王艳芳,苏婉玉,张 琳,等.植物中lncRNAs的研究进展[J].西北植物学报,2018,38(3):582-588

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  • 在线发布日期: 2018-04-23
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