Abstract:As a major environment factor, low temperature affects the geographic distribution and diversity of plants, and threats the sustainable development of agriculture. ICE1 (INDUCER OF CBF EXPRESSION1)CBF (CREPEATBINDING FACTOR) signal pathway functions critical roles not only in plant cold tolerance, but also in plant growth and development. The insight into ICE1CBF pathway improves our understanding about how plants balance growth and cold tolerance. In this review, we summarized the latest advances in research of the sophisticated regulation of ICE1CBF pathway in cold tolerance, and mainly discussed the roles of ICE1CBF pathway in plant growth and development.