Rac proteins of plants belong to Rhorelated GTPase family (ROP family) and play important roles in reactive oxygen species (ROS) production, hormone signal transduction and tissue morphogenesis. Sandalwood (Santalum album Linn.) is a precious and semiparasitic plant with specialized root haustoria to absorb nutrients from other host plants. Based on the fulllength transcriptome data, a Rac protein gene was isolated from Santalum album by RTPCR and named SaRac1. The results showed that： (1) SaRac1 contains a 594 bp opening reading frame, encoding a putative hydrophilic protein of 197 amino acids with molecular weight 21.55 kD and isoelectric point 9.32. (2) Phylogenetic tree analysis showed that the amino acid sequence exhibits high similarity to AtRac1-6, AtRac9 and AtRac11 in Arabidopsis thaliana and belongs to typical Rac I proteins in plants. (3) Sequence alignment indicated the protein has conserved G domains in the Nterminal and CaaL motif in the Cterminal. (4) Subcellular localization analysis showed that SaRac1 localized in the nucleus and cytoplasm. (5) Tissuespecific expression analysis revealed that the transcript level of SaRac1 was higher in roots and haustoria than those in other issues. (6) SaRac1 was induced by 2, 6dimethoxyρbenzoquinoe (DMBQ, an important haustoriuminducing factor) and reached the highest transcript level at 4 h. These results indicate that SaRac1 might be induced by the chemical factor and involved in the development of haustorium.