Abstract:Plants have evolved large families of receptorlike kinases(RLK) to perceive and process external signal to form coordinated responses, which are critical to adapt to various physiological processes and biological metabolism of plants. M/MLDRLKs are unique to plants because of their unique and novel malectinlike domains in their extracellular domain. Recent studies have shown that M/MLDRLKs involved in plant development and biotic/abiotic stress regulation. This article reviews the research history, structural characteristics and biological functions of plant M/MLDRLKs. We systematically reviewed the recent studies on the functions of M/MLDRLKs in regulating plant roots, leaves, flower development and various stress responses. This will provide a reference for elucidating the physiological functions of M/MLDRLKs in the process of plant growth and development.