In order to counteract the invasion of pathogenic microorganisms,plants have evolved a set of immune system to recognize the pathogens and mount defense.The plasma membrane-tethered pathogen recognition receptors (PRRs) and the cytoplasmic NB-LRR immune receptors are responsible for the recognition of the conserved features of pathogens.Following the recognition,the transportation of signals between nucleus and cytoplasm requires the presence of nucleocytoplasmic transport proteins to help the immune proteins and/or their associated signal carries to pass through the nuclear pores.Notably,some types of pathogen effectors,such as transcription activator-like (TAL) effectors,have also been found utilizing the host nucleocytoplasmic transport system to enter nucleus and to activate the expression of host susceptibility genes.In this review,we summarized the recent progresses of nucleocytoplasmic transport in plant innate immunity,including the mechanism of it,the require of plant immunity to it and some protein related to it in plant immunity,to demonstrate its importance in disease resistance.