In this study,one gene encoding ethylene responsive factor binding protein (ERF) was cloned from Salvia miltiorrhiza by RT-PCR,which was named as SmORA1(GenBank accession number:KT359598).SmORA1 DNA sequence consists of 648 bp without introns,and encoding 206 amino acid residues.Bioinformatics analysis showed that SmORA1 contain typical AP2 binding domain of ERF family.The real-time quantitative PCR analysis revealed that SmORA1 was mainly expressed in the roots,furthermore it can be induced by methyl jasmonate (MeJA),abscisic acid (ABA),ethylene (ET),physical wounding and pathogens.While the expression level of SmORA1 was down-regulated under low temperature or dehydration treatment.These results indicated that SmORA1 was involved in plant stress responses,and integrated JA,ET,ABA and pathogen signals in S.miltiorrhiza.