In order to increase rice resistance to blast with more exogenous genes,Sophora flavescens lectin (SFL) encoding lectin which can prohibit the growth of the blast fungus in vitro was introduced into rice cultivar ‘Yunzijing41’ by Agrobacteriummediated transformation method.A lot of transgenic plants were selected by chlorophenolred (CPR) assay and confirmed by PCR.Compared with nontransgenic rice,the transgenic plants showed high resistance to Piricularia oryzae Cav.SFL has broadspectrum antimicrobial activity,so the transgenic rice may has good resistance to variety of pathogenic bacteria.This experiment was laid the foundation for researching on breeding of blast resistance in rice varieties and broaden the diseaseresistant genetic and increase rice blast resistance gene in future.