Plants are susceptible to infect drought stress during growth and development.It is specially significant to the proteomics in the study of physiological mechanisms of plant drought stress by exploring the different proteins and genes under the drought stress conditions.This paper reviewed the concept and research methods of proteomic,and current progress of plant drought stress,included in their photosynthesis and C metabolism,antioxidant enzyme systems,osmoregulation protein,heat shock protein(HSP),late embryogenesis abundant proteins(LEA)and transcription factors etc.At the same time,some proposals were put forward for future research.