The wetland landscape changes of small lakes of Bosten Lake were analyzed from 1996 to 2015 with adoption of landscape conversion coefficient and the model of center of gravity migration, with small lakes of Bosten Lake as research area and adopting the Landsat images in five different periods as main data source. Research results show that: (1) the center of gravity of wetland with surface water and dry land changes dramatically in nearly 20 years, and between 1996 and 2001. The change of center of gravity of wetland with surface water reached the highest value and moved by 10.57 km to the southwest. The maximum change value of center of gravity for dry land appeared between 2001 and 2006 and moved by 8.78 km to the southwest. (2) In nearly 20 years, the water around wetland of small lake area was decreasing gradually, dry land expanded to inside annually and the center of gravity migration of water and dry land moved in a clockwise direction. (3) Stable landscape was the main composition type of study area. In nearly 20 years, accounting for 89.72% of the total types and nonstable landscape in 11.28% of the total type. The wetland landscape change of small lakes of Bosten Lake presented a stable trend gradually. Climatic factors, lake level and human factors were main factors that influence of wetland landscape change in the study area.