Fbox proteins are a protein family containing Fbox motif and in charge of recognizing the substrate to be degraded during ubiquitinproteasome pathway. In order to promote the functional study of Fbox family in Arabidopsis thaliana and other important crops, and draw a complete metabolic network of the family in plants as soon as possible, the present paper focuses on the research progress of Fbox family in A. thaliana reported in recent years, including the amount, type of member of Fbox family and their roles during growth and development, cell signal transduction, biotic and abiotic stress resistance and other physiological processes.