The habitat conditions in the karst area are complex and the ecosystem is fragile and rocky desertification has become an important factor in restricting the development of karst areas. In this paper, we reviewed the stress resistance of biological soil crust in ecosystem and its key role in accelerating soil formation rate, improving surface erosion resistance, improving soil environmental state, regulating precipitation infiltration, changing soil water redistribution pattern, promoting soil microbial derivation and vegetation succession, and improving ecosystem biodiversity. The feedback mechanism of biological soil crusts and karst ecosystems and the application potential of the technology of artificial cultivation crust vegetation for rocky desertification control were demonstrated. In addition, the interaction mechanism between biological soil crusts and ecosystems is the key to studying ecological management in karst areas. The relationship between biological soil crusts and ecosystems is a dynamic process and requires longterm uninterrupted multidimensional monitoring. The researches on mechanism between biological soil crust and karst habitat and their interaction in karst processes, the stress tolerance of biological soil crust in karst areas and artificial cultivation technology and mechanism in karst habitat are recommended to strengthen.