Based on the field survey data, the relationship between A. squarrosum communitys distribution and soil factors in southeast margin of Badain Jaran Desert was discussed by quantitative classification and ordination, in order to provide theoretical support for artificial domestication and cultivation of A. squarrosum. The results showed that A. squarrosum community consists of 21 species, including 8 species of Amaranthaceae, 3 species of gramineae, 3 species of Compositae, 2 species of Tamaricaceae, each 1 species of Zygophyllaceae, Fabaceae, Solanaceae and Plumbaginaceae. TWINSPAN divided the A. squarrosum community into seven associations. The soil moisture decreased from 5.12% to 1.01%, and soil clay content gradually decreased from 6.32% to 2.53% in the process of associations Ⅰ to Ⅶ. The soil sand content of cluster Ⅰ increased from 78.25% to 89.84% of cluster Ⅵ and 87.78% of cluster Ⅶ. Soil organic matter, total nitrogen, available phosphorus, pH and electrical conductivity fluctuated in each cluster. CCA ordination results showed that soil factors explained 30.8 % of the total variation of A. squarrosum associations. The order of variance explained by soil factors was soil moisture (6.8%)> pH(5.3%) > available phosphorus (4.4%) > soil organic matter (4.4%) > total nitrogen (3.6%) > silt(2.3%) >electrical conductivity (2.2%) > sand(1.9%)。Among them, pH, soil moisture, organic matter, and available phosphorus were important environmental regulatory factors that affect the distribution of A. squarrosum communities. In addition to ensuring the normal water supply, the artificial cultivation of A. squarrosum should also focus on the supplement of soil organic matter and available phosphorus.