Terpenoids metabolism is one of the most important pathways of secondary metabolism in plant.The regulatory mechanisms that modulate this metabolic route will determine plant growth and development,resistance,quality and other aspects.The terpene precursors are synthesized by the 2CMethylDErythritol4Phosphate (MEP) pathway in plant plastids.Recent studies have shown that,many genes involved in MEP pathway are not only regulated by multiple genes encoding and the transcript level,but also by posttranscriptional mechanism.Posttranscriptional regulation is a novel regulation mechanism described recently for this way and the mechanism is not clear.We review here various regulatory mechanisms of MEP pathway in plant,especially the mechanism and signal molecular that may be involved in posttranscriptional regulation,which may provide the theory basis for the research of regulation in this pathway.