Actin depolymerizing factor (ADF/cofilin) is one of the important actin-binding proteins.In plant cells,ADF/cofilin plays an indispensable role on signal transduction during plant development and responds to external stimulus by combining with actin,and by this way controls various biological activities.This paper summarizes the sequence characteristics of ADF/cofilin family,their localization,functions on cell growth,abiotic and biotic stress resistance and regulation mechanism of Phosphorylation,pH and PIP2,to lay the foundation for revealing ADF/cofilin new function mechanism in stress resistance.